Role of Mitophagy in Exercise-induced Adaption of Insulin Resistance

This study used the method of literature review to explore the role of mitophagy in insulin resistance which was improved by exercise. The results show that mitochondrial dysfunction caused by oxidative damage is an important reason for insulin resistance. Exercise can activate mitophagy, decrease dysfunctional mitochondria and finally ameliorate insulin resistance. The specific mechanism, however, needs to be further studied.