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中国高校百佳科技期刊

易筋经对老年人认知功能和外周血BDNF水平的影响

Intervention Study of Yi Jin Jing Effecting Cognitive Function and Peripheral Blood BDNF Level of Old People

  • 摘要:
      目的  研究易筋经对老年人认知功能和外周血脑源性神经营养因子(BDNF)含量变化的影响,探寻有效提高老年人认知功能的健身手段和可能的机制。
      方法  采用整群随机抽样方法,在上海市部分社区招募志愿者,均为健康老年人(60~69岁),分为对照组(n=35)和实验组(n=38);实验前后分别对2组受试者进行认知能力评估,并采集血液样本进行BDNF测定。
      结果  实验前,2组受试者的认知能力评分和血液BDNF水平均无显著性差异;实验后,易筋经干预组的认知能力评分显著高于对照组,且与实验前相比,干预组的认知能力评分显著增高;外周血BDNF水平表现出了与认知能力评分结果相一致的变化趋势;相关性分析结果表明,易筋干预组的老年人认知水平与其外周血BDNF水平呈显著正相关。
      结论  3个月的易筋经运动干预可显著改善健康老年人的认知功能,且与外周血BDNF的浓度水平有关。

     

    Abstract:
      Objectives  To study the effects of Chinese traditional sports yi jin jing on cognitive function and peripheral blood of old people; to detect the effective fitness means for improving cognitive function of old people and possible influence mechanism.
      Methods  cluster random sampling method was used, and 60-69 years old healthy people in some communities in Shanghai were recruited and divided into 2 groups:the control group and the test group.The control group engaged in daily physical activity without any sports exercise, while the test group were subjected to yi jin jing exercise intervention for three months.Before and after the experiment, the cognitive function was tested and the blood sample was collected for BDNF analysis.
      Results  Before the experiment, there was no significant difference in the subjects' cognitive level score and the peripheral blood BDNF level between the control and the test group.After the experiment, the cognitive level score of intervention group subjects was significantly higher than that of the control group, with a significantly higher cognitive level score than that before the experiment.The variation trend of peripheral blood BDNF level was consistent with the cognitive level score, and the correlation analysis showed that the cognitive function improvement was positively correlated to the increase of peripheral blood BDNF level.
      Conclusions  Three months yi jin jing exercise can obviously improve the cognitive function of healthy old people, and this improvement is related to the increase in peripheral blood BDNF level.

     

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