Abstract:
It is to determine if oligosaccharides supplements improves rats with estrogen cycle inhibition when they are neither changed by the exercise load nor used drug intervention, but with supplemented carbohydrates as energy to intervene in rats with estrogen cycle inhibition.
Methods Thirty-six female Sprague-Dawley rats (two months old) were randomly divided into four experimental groups:Negative control group (Nco), 9-weeks exercise as model for AMI (Pco), post-AMI rest recovery group (Res), oligosaccharide intervention group (Oli).All rats were sacrificed at the end of 9-weeks.
Results After three weeks of intervention:1) Res and Oli group increased the number of vaginal exfoliated cells, and began to appear non-nuclear surface cells; 2) Res and Oli groups' PRL level was significantly lower than Pco group, but GnRH, FSH, LH, E2 and P level was significantly higher than Pco group.
Conclusion By added oligosaccharides to rats with estrogen cycle inhibition, the available energy could be increased and the estrous cycle restrain in rats could be improved consequently.